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Question

The Cahn-Ingold-Prelog (CIP) priorities of the groups and the absolute configuration (R/S) of the following compound are:


A
CH2OH>CH(CH3)2>CH=CH2>CH3 and S
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B
CH2OH>CH=CH2>CH(CH3)2>CH3 and S
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C
CH2OH>CH=CH2>CH(CH3)2>CH3 and R
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D
CH2OH>CH(CH3)2>CH=CH2>CH3 and R
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Solution

The correct option is B CH2OH>CH=CH2>CH(CH3)2>CH3 and S
According to CIP rule the priorities of the groups are
CH2OH>CH=CH2>CH(CH3)2>CH3


Here the counting of substituents from 1 to 3 is anticlockwise keeping the lowest priority group below the plane. So, the absolute configuration of the given compound is ‘S’.

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