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Question
The components that form the core of the nucleosome are
The components that form the core of the nucleosome are
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Solution
The correct option is D H2A, H2B, H3, H4
Nucleosomes are fundamental organizational units of chromatin which appear as “beads-on-a-string” arrangement. Here beads represent complexes of histones and DNA. Each bead contains core of histone octamer: two copies each of H2A, H2B, H3, and H4; out of 200 bp DNA, 146 bp DNA is bound tightly around the histone core and the remainder serve as linker DNA between nucleosomal beads. The H1 histone associates with the linker DNA to pack adjacent nucleosomes together and forms a compact 30-nm chromatin fiber. Correct answer is D.
Nucleosomes are fundamental organizational units of chromatin which appear as “beads-on-a-string” arrangement. Here beads represent complexes of histones and DNA. Each bead contains core of histone octamer: two copies each of H2A, H2B, H3, and H4; out of 200 bp DNA, 146 bp DNA is bound tightly around the histone core and the remainder serve as linker DNA between nucleosomal beads. The H1 histone associates with the linker DNA to pack adjacent nucleosomes together and forms a compact 30-nm chromatin fiber. Correct answer is D.
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