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Question

The connecting link reaction between glycolysis and Krebs cycle is _______.

A
phosphorylation
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B
isomerisation
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C
pyruvate oxidation
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D
dehydration
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Solution

The correct option is C pyruvate oxidation
Aerobic respiration commences with the oxidation of pyruvic acid. This is called link reaction or gateway step as it links glycolysis in cytoplasm and Krebs cycle in mitochondrial matrix. Here pyruvate is oxidised to acetyl CoA which enters the Krebs cycle for further oxidation.

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