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Question

The contribution of Martha Chase and Alfred Hershey is

A
discovery of transforming principle
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B
discovery of the biochemical nature of transforming principle
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C
providing the proof that DNA is genetic material
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D
discovery of DNA
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Solution

The correct option is C providing the proof that DNA is genetic material
Griffith conducted experiments with Streptococcus pneumoniae and discovered the transforming principle that can transform the nonvirulent R strain of bacteria into virulent S strain.

Oswald Avery, MacLeod and McCarty worked to find out the biochemical nature of the ‘transforming principle’ in Griffith's experiment. They concluded that DNA is the transforming principle.

But the unequivocal proof that DNA is the genetic material came from the experiments of Alfred Hershey and Martha Chase (1952). They worked with Escherichia coli and bacteriophage (virus that infects bacteria).

Friedrich Meischer discovered DNA inside the nucleus of pus cells and called it nuclein.

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