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Question

The cyanide ions are toxic because they bind almost irreversibly to the Fe(III) ion in:

A
cytochrome oxidase.
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B
thyroid.
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C
haemoglobin.
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D
cytochrome C.
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Solution

The correct option is B cytochrome C.
The enzyme cytochrome C oxidase, or Complex IV is a large transmembrane protein complex found in bacteria and the mitochondrion of eukaryotes. It is the last enzyme in the respiratory electron transport chain of mitochondria or bacteria located in the mitochondrial or bacterial membrane.
This transfer of electrons, which is necessary for respiration, is blocked when cyanide ion attaches to the enzyme.

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