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Question

The distance between the two strands of a dsDNA is approximately uniform because of the following reason?

A
Presence of phosphodiester bonds
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B
Purine always comes opposite to pyrimidine in a dsDNA
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C
Presence of N-glycosidic linkage
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D
Presence of hydrogen bonds
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Solution

The correct option is B Purine always comes opposite to pyrimidine in a dsDNA
In the complementary base pairing of DNA, the purine always pairs with a pyrimidine. As a result, adenine pairs with thymine with two hydrogen bonds and cytosine pairs with guanine with three hydrogen bonds. This generates approximately a uniform distance between the two strands of the double stranded DNA.

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