Question

The DNA content of individual cells and the number of cells in each phase of a "cell cycle" can be determined using flow cytometry. Which of the following combinations of "phase of a cell cycle and its corresponding DNA content" can be considered normal?
(i) Diploid cells found in the $G_0$ or $G_1$ phase.
(ii) Cells with twice the normal DNA content in the early M phase.
(iii) Cells with intermediate amounts of DNA in the S phase.
(iv) Cells with twice the normal DNA content in the $G_2$ phase.

• A. (i) and (ii)
• B. (ii) and (iii)
• C. (iii) and (iv)
• D. (i), (ii), (iii) and (iv)

Answer 1

Answer: (D)

(i), (ii), (iii) and (iv)

D. (i), (ii), (iii) and (iv)

Solution : The diploid cells found in the G0 and G1 phase before starting the G2 or M phase but before anaphase. Cells with twice the normal DNA is in G2 or M phase that is mitosis phase. The S phase is characterized by intermediate DNA when the DNA starts replicating itself, till the entire replication process is complete.

So the correct answer is " (i), (ii), (iii) and (iv)".