The drug colchicine has an inhibitory effect on cell cycle in which stage?

G_{1}

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G_{2}

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Solution

The correct option is C M
Colchicine is a mitotic inhibitor or cell division. This drug disrupts microtubules, which are structures that pull the chromosomes apart when a cell divides.
Interphase is composed of G1 phase (cell growth), followed by S phase (DNA synthesis), followed by G2 phase (cell growth). At the end of interphase comes the mitotic phase.
The basic events of mitosis include chromosome condensation, formation of the mitotic spindle, and attachment of chromosomes to the spindle microtubules.
So when colchicine is added to cultured cells, the cells enter mitosis and gets arrested with condensed chromosomes. So the correct option here is the M phase.

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