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Question

The enzyme that helps human immunodeficiency virus (HIV) to integrate its own DNA into a host cell's genome is

A
DNA polymerase
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B
Helicase
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C
Primase
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D
Ligase
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E
Reverse transcriptase
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Solution

The correct option is E Reverse transcriptase
HIV is RNA retrovirus and synthesizes DNA using their RNA as a template via reverse transcription; a process carried out by reverse transcriptase enzyme. The synthesized DNA, cDNA, is inserted into a host and transcribed into RNA which in turn is translated into polypeptides. DNA polymerase, ligase, primase, and helicase are enzymes of DNA replication. Thus, the correct answer is option E.

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