Question

The enzyme which catalyses the formation of glutamine from its substrate belongs to category

• A. Hydrolases
• B. Transferases
• C. Ligases
• D. Lyases

Answer 1

The correct option is C Ligases

Glutamine is formed as a result of ligation reaction involving the condensation of glutamate and ammonia. The reaction is catalysed by enzyme glutamine synthetase which is a type of ligase and plays important role in the metabolism of nitrogen. Ligases are a category of enzymes which catalyse the linking together of two compounds. The enzyme utilizes ammonia produced from amino acid degradation and hotoresiration. The reaction involve the ATP dependent condensation of ammonia with glutamate. Hydrolases are enzymes which catalyse hydrolysis of ester, ether, peptide, glycosidic bonds.

Transferases are enzymes which catalyse the transfer of a group, G (other than hydrogen) between two substrates. Lyases are the enzymes that catalyse removal of groups from substrates by mechanisms other than hydrolysis leaving double bonds. Thus, the correct answer is option C.