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Question

The fate of pyruvic acid during aerobic respiration is

A
Lactic acid fermentation
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B
Alcoholic fermentation
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C
Oxidative decarboxylation
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D
Oxidative phosphorylation
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Solution

The correct option is C Oxidative decarboxylation
During aerobic respiration, pyruvic acid which is formed during glycolysis enters the mitcohondrial matrix. It undergoes oxidative decarboxylation to produce CO2 and NADH. The product combines with sulfur-containing co-enzyme A to form acetyl CoA. This reaction is catalyzed by an enzyme complex pyruvate dehydrogenase. This step is called link reaction or gateway step as it links glycolysis with Krebs' cycle.

Pyruvicacid+COA+NAD+Mg2+−−−−−−−−−−−−−−PyruvatedehydrogenaseAcetylCoA+CO2+NADH+H+
So the correct answer is 'Oxidative decarboxylation'.

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