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Question
The female hormone inhibin is secreted by
The female hormone inhibin is secreted by
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Solution
The correct option is A Corpus luteum
In human males, the Sertoli cells have been found to produce two chemicals, inhibin and activin, which appear to play a large role in regulating FSH concentrations.
In human females, the menstrual cycle has three phases.Menstruation, Follicular and Luteal phase. As the follicular phase ends, estrogen secretion is at a maximum level and the granulosa cells of the dominant follicle begin to produce inhibin and progesterone. Earlier in the follicular phase, low levels of estrogen exerted an inhibitory effect or negative feedback on the release of GnRH and gonadotropins. Now at these elevated levels, estrogen becomes stimulatory or a positive feedback and along with the elevated levels of progesterone, increases the sensitivity of the pituitary gland to GnRH. This causes a dramatic increase in LH secretion, an event known as the LH surge. FSH, which is no longer needed, also surges, but to a lesser degree, probably due to the influence of inhibin. After ovulation, the corpus luteum produces increasing amounts of progesterone and estrogen. Progesterone becomes the dominant hormone. Although estrogen levels increase moderately, they never reach the preovulatory levels. This cocktail of estrogen and progesterone exerts a negative feedback on the hypothalamus and, with the help of inhibin, the anterior pituitary gland. This negative feedback essentially shuts off GnRH production by the hypothalamus and gonadotropin release from the anterior pituitary, effectively blocking the ovary from initiating follicle development.Therefore, the correct answer is option C.
In human males, the Sertoli cells have been found to produce two chemicals, inhibin and activin, which appear to play a large role in regulating FSH concentrations.
In human females, the menstrual cycle has three phases.
Menstruation, Follicular and Luteal phase.
As the follicular phase ends, estrogen secretion is at a maximum level and the granulosa cells of the dominant follicle begin to produce inhibin and progesterone. Earlier in the follicular phase, low levels of estrogen exerted an inhibitory effect or negative feedback on the release of GnRH and gonadotropins. Now at these elevated levels, estrogen becomes stimulatory or a positive feedback and along with the elevated levels of progesterone, increases the sensitivity of the pituitary gland to GnRH. This causes a dramatic increase in LH secretion, an event known as the LH surge. FSH, which is no longer needed, also surges, but to a lesser degree, probably due to the influence of inhibin.
After ovulation, the corpus luteum produces increasing amounts of progesterone and estrogen. Progesterone becomes the dominant hormone. Although estrogen levels increase moderately, they never reach the preovulatory levels. This cocktail of estrogen and progesterone exerts a negative feedback on the hypothalamus and, with the help of inhibin, the anterior pituitary gland. This negative feedback essentially shuts off GnRH production by the hypothalamus and gonadotropin release from the anterior pituitary, effectively blocking the ovary from initiating follicle development.
Therefore, the correct answer is option C.
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