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Question

The figure given below shows three velocity substrate concentration curves for an enzyme reaction. What do the curves A, B, and C depict respectively?

A
A-normal enzyme reaction
B-competitive inhibition
C-non-competitive inhibition
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B
A-enzyme with an allosteric modulator added
B-normal enzyme activity
C-competitive inhibition
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C
A-enzyme with an allosteric stimulator
B-competitive inhibitor added
C-normal enzyme reaction
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D
A-normal enzyme reaction
B-non-competitive inhibitoradded
C-allosteric in hibitor added
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Solution

The correct option is A A-normal enzyme reaction
B-competitive inhibition
C-non-competitive inhibition
In the given figure, curve A shows normal enzyme reaction, while curve B shows a competitive inhibition reaction, in which competitive inhibitors that resemble the substrate molecules, bind to the active site of the enzyme, whereas, curve C shows non-competitive inhibition reaction, in which the inhibitor binds to a part of the enzyme or enzyme substrate complex, other than the active site, known as the allosteric site.

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