The first antibody to appear in serum following stimulation by antigen is

IgG

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IgM

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IgE

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IgA

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Solution

The correct option is A IgM
IgM is the first class of antibody to appear on the surface of a developing B cell.
It is also the major class secreted into the blood in the early stages of a primary antibody response, on first exposure to an antigen.
IgM antibody appears first, followed by IgA on mucosal surfaces or IgG in the serum.
Hence, The first antibody to appear in serum following stimulation by antigen is IgM.
So, the correct answer is 'IgM'.

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