Question

The first clinical gene therapy was given for treating?

• A. Chicken pox
• B. Rheumatoid arthritis
• C. Diabetes mellitus
• D. Adenosine deaminase deficiency

Answer 1

The correct option is D

Adenosine deaminase deficiency

The correct option is D.

Explanation for correct option:

1. Adenosine deaminase (ADA) deficiency is an inherited disorder that damages the immune system and causes severe combined immunodeficiency (SCID).
2. People with SCID lack virtually all immune protection from bacteria, viruses, and fungi.

Explanation for the incorrect options:

Option A:

1. Chickenpox, also known as varicella, is a highly contagious disease caused by the initial infection with varicella zoster virus (VZV).
2. The disease results in a characteristic skin rash that forms small, itchy blisters, which eventually scab over.
3. It usually starts on the chest, back, and face.

Option C:

1. A disease in which the body does not control the amount of glucose (a type of sugar) in the blood and the kidneys make a large amount of urine.
2. This disease occurs when the body does not make enough insulin or does not use it the way it should.

Option B:

1. An autoimmune disease that causes pain, swelling, and stiffness in the joints, and may cause severe joint damage, loss of function, and disability.
2. The disease may last from months to a lifetime, and symptoms may improve and worsen over time.

Final answer: The first clinical gene therapy was given for treating Adenosine deaminase deficiency.