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Question

The first codon discovered by Nirenberg and Matthaei was

A
CCC
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B
GGG
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C
UUU
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D
AAA
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Solution

The correct option is C UUU
Marshall Nirenberg and Heinrich J. Matthaei were the first to elucidate the nature of a codon in 1961 at the National Institutes of Health. They used a cell-free system to translate a poly-uracil RNA sequence and discovered that the polypeptide that they had synthesized consisted of only the amino acid phenylalanine.They thereby deduced that the codon UUU specified the amino acid phenylalanine.

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