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Question
The first compound to enter TCA cycle along with Acetyl CoA is
The first compound to enter TCA cycle along with Acetyl CoA is
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Solution
The correct option is B oxaloacetic acid
Krebs cycle can be defined as a stepwise, oxidative and cyclic degradation of acetyl CoA derived from the end product of glycolysis i.e. pyruvate. Krebs’ cycle starts with condensation of acetyl group (acetyl CoA) with oxaloacetate (4- carbon compound) in the presence of a condensing enzyme citrate synthase to form a tricarboxylic, 6- carbon compound called citric acid. It is the 1st product of Krebs cycle. CoA is liberated. Hence oxalo acetic acid is the 1st member of the TCA cycle.
Krebs cycle can be defined as a stepwise, oxidative and cyclic degradation of acetyl CoA derived from the end product of glycolysis i.e. pyruvate. Krebs’ cycle starts with condensation of acetyl group (acetyl CoA) with oxaloacetate (4- carbon compound) in the presence of a condensing enzyme citrate synthase to form a tricarboxylic, 6- carbon compound called citric acid. It is the 1st product of Krebs cycle. CoA is liberated. Hence oxalo acetic acid is the 1st member of the TCA cycle.
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