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Question

The first concluding proof that DNA is the hereditary material was given by:

A
Avery, MacLeod and McCarty
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B
Hershey and Chase
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C
Griffith
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D
Watson and Crick
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Solution

The correct option is A Avery, MacLeod and McCarty
Griffith did discover the “transforming principle”, although he couldn’t identify what it was. It was Avery, MacLeod and McCarty who worked together to identify the biochemical nature of Griffith’s transformation experiments. Their team was the first to observe that DNA is the hereditary material. They treated the purified biochemicals of heat-killed S strain separately using the enzymes DNAse, RNAse and proteinase. They observed that when DNAse was added, transformation could not happen (i.e., in the absence of DNA); this indicated that DNA was the transforming principle.

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