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Question

The first restriction endonuclease was

A
EcoRII
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B
HindII
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C
HindIII
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D
AvaI
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Solution

The correct option is A HindII
A restriction enzyme (or restriction endonuclease) is an enzyme that cuts DNA at or near specific recognition nucleotide sequences known as restriction sites. Werner Arber, Hamilton Smith, and Daniel Nathans received the 1978 Nobel Prize in Physiology or Medicine for developing the smaller names for the restriction enzymes. HindII was the first restriction enzyme to be isolated. This enzyme was first isolated from Haemophilus influenzae Rd strain II. So, the enzyme was shortly labelled as HindII.
Thus, the correct answer is option B.

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