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Question

The foreign serum interacts with the antibodies and forms immune complexes.These immune complexes get deposited on the endothelial lining of blood vessels in various parts of the body causing an inflammatory reaction.
The above statement can be related to which of the following response?

A
Hypersensitivity I
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B
Hypersensitivity II
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C
Hypersensitivity III
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D
Hypersensitivity IV
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Solution

The correct option is C Hypersensitivity III
The excess of antigen agglutinates and lead to the formation of small immune complexes and are not cleared from the circulation causes Type III hypersensitivity. It involves soluble antigens that are not bound to cell surfaces. When these antigens agglutinate and insert themselves into small blood vessels, joints, and glomeruli, causing severe symptoms. The foreign serum interacts with the antibodies and forms immune complexes.These immune complexes get deposited on the endothelial lining of blood vessels instead of getting cleared from the circulation and causes severe symptoms.
So, the correct answer is option C.

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