The function of IgE is

Mediate in allergic response

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Activation of B-cells

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Protection from inhaled and ingested pathogen

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Stimulation of complement system, passive immunity to foetus

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present on lymphocytes surface as receptors

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Solution

The correct option is A Mediate in allergic response
Immunoglobulin E (IgE) is a type of antibody that has only been found in mammals. IgE is synthesised by plasma cells. It plays an essential role in type I hypersensitivity, which manifests in various allergic diseases, such as allergic asthma, rhinitis etc. It also plays a pivotal role in responses to allergens, such as anaphylactic drugs, bee stings, and antigen preparations used in desensitization immunotherapy.
So, the correct answer is 'Mediate in allergic response'.

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\begin{matrix} Column A & Column B 1. Bone marrow & p. Secondary lymphoid organ 2. Lymph nodes & q. Antibody production 3. IgE & r. Primary lymphoid organ 4. B-lymphocytes & s. Allergic responses \end{matrix}

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