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Question

The function/s of the renin produced by kidney is/are

A
Stimulate hematopoiesis
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B
Change angiotensinogen into angiotensin
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C
Influence ultrafiltration
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D
All of the above
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Solution

The correct option is C All of the above
  • Decreased blood pressure, low sodium levels are the stimuli for the production of renin from the kidney.
  • The renin secreted has enzymatic activity and is an important part of the renin-angiotensin-aldosterone system (RAAS).
  • The RAAS plays an important role in regulating the cardiac output and arterial pressure. It does it by regulating the ultrafiltration in the kidneys.
  • The main function of renin in the RAAS system is the conversion of angiotensinogen to angiotensin I (proteolytic activity).
  • Though the mechanism is not clearly understood the renin-angiotensin system (RAS) also plays an important role in the hematopoiesis.
Thus renin performs all the three functions. Hence, the correct option is D.

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