Question

The generation of excitation-contraction coupling involves all the following events except

• A. Generation of end-plate potential
• B. Release of calcium from troponin
• C. Formation of cross-linkages between actin and myosin
• D. Hydrolysis of ATP to ADP

Answer 1

The correct option is B Release of calcium from troponin

Excitation-contraction coupling is a process that relates to the electrical excitation through generation of force and contraction in the skeletal muscles. The central process that brings about the excitation-contraction is calcium mobilization. The process involves inward flux of extracellular calcium ions through L-type calcium channels, calcium induced calcium release through sacroplasmic reticulum, with the increase in concentration of intracellular calcium, the calcium ions get bound to protein troponin and myosin binds to actin.

Hence B is the correct option.