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B
Autosome 16
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C
Both A and B
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D
Chromosome 21
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Solution
The correct option is C Both A and B The α-like globin genes are located on chromosome 16, whereas the β-like globin genes are on chromosome 11. The latter results were obtained by hybridizing a solution of total cellular DNA from the various somatic hybrid cells to radioactive cDNAs, synthesized from α- and β-globin mRNAs by reverse transcriptase.