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Question
The given compound is obtained by Claisen condensation of ?
The given compound is obtained by Claisen condensation of ?
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Solution
The correct option is C Ethyl-4-methyl pentanoate
Ester undergoes self condensation in presence of strong base to give β-ketoester. This reaction is called Claisen condensation reaction.
Mechanism of Claisen condensation reaction:
1. Enolate formation : The strong base will abstract the acidic α-hydrogen to form the enolate ion.
2. Nucleophile attack: Formed enolate will attack the carbonyl carbon of another ester molecule and leaving group (-OR) will leave the compound to form β− ketoester.
The given product is a self condensation product and from the product we can predict that the leaving group is −OEt and the enolate ion formed at α- position of ester.
Hence, the possible reactant of the claisen condensation reaction is Ethyl-4-methyl penatanoate.
Ester undergoes self condensation in presence of strong base to give β-ketoester. This reaction is called Claisen condensation reaction.
Mechanism of Claisen condensation reaction:
1. Enolate formation : The strong base will abstract the acidic α-hydrogen to form the enolate ion.
2. Nucleophile attack: Formed enolate will attack the carbonyl carbon of another ester molecule and leaving group (-OR) will leave the compound to form β− ketoester.
The given product is a self condensation product and from the product we can predict that the leaving group is −OEt and the enolate ion formed at α- position of ester.
Hence, the possible reactant of the claisen condensation reaction is Ethyl-4-methyl penatanoate.
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