The gonadotropin releasing hormone (GnRH) released by the ___(i)_stimulates the _(ii)____ to release _(iii)____ and _(iv). The LH stimulates the Leydig cells to produce(v)__.

(i) hypothalamus (ii) pituitary (iii) FSH (iv) estrogen (v) testosterone

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(i) hypothalamus (ii) pituitary (iii) LH (iv) FSH (v) testosterone

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(i) pituitary (ii) hypothalamus (iii) LH (iv) FSH (v) testosterone

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(i) hypothalamus (ii) pituitary (iii) LH (iv) testosterone (v) FSH

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Solution

The correct option is B
(i) hypothalamus (ii) pituitary (iii) LH (iv) FSH (v) testosterone

The gonadotropin releasing hormone (GnRH) released by the neurons of hypothalamus stimulates the pituitary to release gonadotropins.

There are two important gonadotropins released from the pituitary: luteinising hormone or LH and follicle stimulating hormone or FSH.

LH stimulates the Leydig cells to produce testosterone which is considered as the most important male hormone. It is responsible for the growth and development of reproductive organs as well as for the development of secondary sexual characteristics.

The FSH in turn stimulates the Sertoli or nurse cells present in the seminiferous tubules to secrete substances important for sperm development and nourishment.

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The gonadotropin releasing hormone (GnRH) released by the _____(i)_____stimulates the ___(ii)______ to release ___(iii)______ and _____(iv)______. The LH stimulates the Leydig cells to produce____(v)______.

The gonadotropin releasing hormone (GnRH) released by the _____(i)_____stimulates the ___(ii)______ to release ___(iii)______ and _____(iv)______. The _____(iii)____ stimulates the leydig cells to produce____(v)______. The ____(iv)___ stimulates the sertoli cells to secrete substances important for sperm development.

Q. Match the following hormones with their functions.

\begin{matrix} A. FSH & 1. Stimulates Leydig cells of testes B. Luteinizing hormone & 2. Responsible for the release of FSH, LH C. Gonadotropin releasing hormone & 3. Stimulates spermatogenesis \end{matrix}

Q. Testosterone is a steroid hormone produced by all vertebrate animals and, in humans and other mammals, it is secreted in large amounts by the testes of males and to a much lesser extent, the ovaries of females. In adult males, testosterone plays a key role in the development of reproductive organs and it promotes the secondary sexual characteristics of body and facial hair, increased muscle and bone mass, and a deep voice. Testosterone, like all hormones, works via long distance signaling and is regulated by other hormones as illustrated below:

Figure 1:

Testosterone regulation by cooperation between the hypothalamus, pituitary, and testicular endocrine glands. The major regulatory hormones involved are luteinizing hormone (LH), follicle-stimulating hormone (FSH) and gonadotropin-releasing hormone (GnRH).

When testosterone levels are low, gonadotropin-releasing hormone (GnRH) is released by the hypothalamus, which in turn stimulates the pituitary gland to release FSH and LH. FSH and LH then stimulate the testis to produce testosterone.
How is homeostasis achieved when testosterone levels begin to rise?

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