The hormone secreted by which of the following gland is responsible for maintaining the basal metabolic rate of the body?
A
Thyroid
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B
Pancreas
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C
Parathyroid
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D
Adrenal medulla
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E
Anterior pituitary
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Solution
The correct option is B Thyroid The basal metabolic rate of the body is controlled by the hormones T3 (triiodothyronine) and T4 (thyroxine), produced by the thyroid gland in response to the thyroid stimulating hormone (TSH), produced by the anterior pituitary. These hormones are transported across the plasma membrane of target cells where they bind to receptors on the mitochondria, resulting in increased ATP production. In the nucleus, T3 and T4 activate genes involved in energy production and glucose oxidation. This results in increased rates of metabolism and body heat production. This is known as the hormone's calorigenic effect.