The hormone which regulates the amount of glucose in the blood by converting excess of glucose into glycogen (glycogenesis) __(1)__. The hormone which regulates glucose in the blood by converting glycogen (glycogenolysis) back to glucose whenever required is __(2)__.
Insulin and Glucagon
1. Insulin is a protein hormone produced by Beta-cells of islets of Langerhans. It regulates the amount of glucose in the blood by converting excess of glucose into glycogen (glycogenesis) which can be stored in the liver and muscles. Lack of insulin, therefore, results in excess glucose in the blood (hyperglycemia) and it starts appearing in urine. This condition is known as diabetes mellitus.
2. Glucagon is also protein hormone produced by Alpha-cells of islets of Langerhans. It also regulates the amount of glucose in the blood by converting glycogen back to glucose whenever required. Thus, its effect is opposite to that of insulin.