The i-gene and structural gene codes for protein/enzymes in Lac operon. Choose the correct option based on the product formed by these genes.

i - Repressor, z -

β

-galactosidase, y - Permease, a - Transacetylase

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i - Inhibitor, z - Repressor, y - Transacetylase, a - Permease

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i - Inducer, z -

β

-galactosidase, y - Permease, a - Repressor

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i -

β

-galactosidase, z - Repressor, y - Permease, a - Transacetylase

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Solution

The correct option is A i - Repressor, z - $β$ -galactosidase, y - Permease, a - Transacetylase
In Lac operon i- gene codes for the repressor protein.
The repressor binds with the operator gene in the absence of lactose and suppresses the transcription.

The lac operon contains three structural genes: lac Z, lacY and lac A. All three structural genes produce enzymes that are essential for the metabolism, entry and breakdown of lactose into its smaller monomeric units such as the glucose and galactose.
z - $β$ -galactosidase - digests lactose
y - Permease - increases permeability of lactose
a - Transacetylase - plays an important role in lactose utilisation

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In lac operon, ‘i' gene codes for

\begin{matrix} C o l u m n I & C o l u m n I I p . R e g u l a t o r g e n e & i . B i n d i n g s i t e f o r r e p r e s s o r p r o t e i n q . O p e r a t o r g e n e & i i . C o d e (s) f o r t h e p r o t e i n o f t h e e n z y m e s r . P r o m o t e r g e n e & i i i . C o d e (s) f o r r e p r e s s o r p r o t e i n s . S t r u c t u r a l g e n e s & i v . B i n d i n g S i t e f o r R N A p o l y m e r a s e \end{matrix}

Column-I	Column-II
(A) Structural gene	(i) Binding site for a repressor protein
(B) Operator gene	(ii) Codes for a repressor protein
(C) Promoter gene	(iii) Induce lactose transport from the medium
(D) Regulator gene	(iv) Codes for protein enzyme
	(v) Binding site for RNA polymerase

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