The inflammatory response in an allergy is caused by the release one of the following by mast cells.
A
Histamines
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B
Antibodies
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C
Antigen
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D
None of the above
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Solution
The correct option is A Histamines Histamine is a nitrogenous compound that acts as a neurotransmitter and involved in local immune responses i.e., inflammatory response. When the pathogen enters into the body, as part of an immune response to foreign pathogens, histamine is produced by basophils and by mast cells found in nearby connective tissues. Histamine increases the permeability of the capillaries to white blood cells and some proteins to allow them to engage pathogens in the infected tissues.