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Question

The kidney regulates acid-base balance by each of the following except.

A
Active reabsorption of H+
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B
Reabsorbing filtered bicarbonates
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C
Acidifying the urine by H+ secretion
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D
Excreting ammonium salts
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E
Both B and C
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Solution

The correct option is E Both B and C

The kidneys have two very important roles in maintaining the acid–base balance: They reabsorb bicarbonate from urine. They excrete hydrogen ions into urine.The kidneys are slower to compensate than the lungs, but renal physiology has several powerful mechanisms to control pH by the excretion of excess acid or base. The major, homeostatic control point for maintaining a stable pH balance is renal excretion. Bicarbonate (HCO3−) does not have a transporter, so its reabsorption involves a series of reactions in the tubule lumen and tubular epithelium. In response to acidosis, the tubular cells reabsorb more bicarbonate from the tubular fluid, and the collecting duct cells secrete more hydrogen and generate more bicarbonate, and ammoniagenesis leads to an increase in the formation of the NH3buffer.

So, the correct option is 'Both B and C'.


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