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Question

The local folding of polypeptide chains happen in which of the following structures?

A
Primary protein structure
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B
Secondary protein structure
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C
Tertiary protein structure
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D
Quaternary protein structure
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Solution

The correct option is B Secondary protein structure
Several amino acids form a peptide bond to give rise to the primary structure. It is a linear polypeptide chain which further undergoes local folding and forms hydrogen bonds which results in the secondary structure of protein. Local folding refers to the formation of bonds within the polypeptide chain due to the interactions between the atoms of the chain. The further three dimensional folding of the secondary structure with the formation of disulphide bonds gives rise to the tertiary structure. Quaternary protein structure consists of more than one polypeptide chain.

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