The correct option is B CFCs
Ozone-depleting substances (ODS) are substances that react with ozone present in the stratosphere and destroy the same. The major Ozone-depleting substances are chlorofluorocarbons (14% of total depletion), nitrogen oxides (3.5% depletion), sulphur dioxide, halon, carbon tetrachloride, methyl chloroform, chlorine, etc.