The correct option is A Co-factors of Enzymes
Answer is option A i.e. "Co-factors of Enzymes"
Micro-elements work as non-protein cofactor in enzymes. Zn, Cu, Fe, Mg, Mn, etc are some mineral elements which acts as a cofactor. These ions attach to the enzyme and activate the enzyme. It brings a conformational change in the structure of an enzyme which eventually accelerate the reaction.