The mature mammalian red blood cells are incapable of further division because

DNA sequences are redundant

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The nuclei are lobed

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They lack nuclei

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The mitotic apparatus is absent

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Solution

The correct option is B They lack nuclei
Because of the lack of nuclei and organelles, mature red blood cells do not contain DNA and cannot synthesize any RNA, and consequently can not divide and have limited repair capabilities.
So, the correct option is C. (They lack nuclei)

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