Question

The medullary interstitial fluid has a very high osmolarity which is maintained by:

• A. Movement of NaCl from descending limb of Henle's loop into medullary interstitium
• B. Uric acid and H+ present in interstitium
• C. Movement of $K^{+}$ and $C{l}^{–}$ from DCT into peritubular capillaries
• D. Movement of urea from PCT into medullary interstitium

Answer 1

The correct option is A Movement of NaCl from descending limb of Henle's loop into medullary interstitium

Development and maintenance of hyperosmolarity of medullary interstitium depends upon the net transport of NaCl across the wall of ascending limb of Henle's loop into the medullary interstitium from the lumen.