The Mitchell or charismatic hypothesis predicts the __________________________.
A
Existence of a higher pH in the endoplasmic reticulum than in the cytosol
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B
Symmetrical distribution of ATPase of the inner membrane of the mitochondria
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C
Synthesis of ATP as protons flow along a gradient across inner mitochondrial membrane
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D
Absence of ATPase in the inner mitochondrial membrane
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Solution
The correct option is C Synthesis of ATP as protons flow along a gradient across inner mitochondrial membrane The chemiosmotic hypothesis was proposed by Peter Mitchell. This hypothesis stated that a proton-motive force was responsible for driving the synthesis of ATP. In this hypothesis, protons would be pumped across the inner mitochondrial membrane as electrons went through the electron transfer chain.