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Question

The most abundant and the smallest antibody is/are

A
IgG
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B
IgM
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C
IgD & IgG
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D
IgA
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Solution

The correct option is A IgG
IgG is the most abundant class of immunoglobulins in the body constituting about 70-80% of the antibodies in the blood. It is the smallest antibody with minimum molecular weight.
Specific antibodies are produced during the initial infection or antigen exposure. IgG is the only maternal antibody that can cross the placenta and give natural passive immunity to the growing foetus.
Antibody types Concentration in serum
IgG 80-85%
IgA 10-15%
IgM 5-7%
IgD 0.3%
IgE 0.02%

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