Question

The most appropriate reagent for the following stereoselective reduction is:

• A. $\text{NaB}{\text{H}}_{\text{4}}$
• B. $\text{E}{\text{t}}_{\text{2}}\text{BOMe,}\text{NaB}{\text{H}}_{\text{4}}\text{,}{\text{H}}_{\text{2}}{\text{O}}_{\text{2}}$
• C. $\text{LiAl}{\text{H}}_4$
• D. $\text{M}{\text{e}}_{\text{4}}\text{NBH}{\left(\text{OAc}\right)}_{\text{3}}$

Answer 1

The correct option is A $\text{NaB}{\text{H}}_{\text{4}}$

$NaB{H}_4$ has ability to deliver $H^{-}$ ion intermolecularly to carbonyl carbon, it can give stereospecific product.