The most popularly known blood grouping is the ABO grouping. It is named ABO and not ABC because ‘O’ in it refers to having
No antigens A and B on RBCs
Landsteiner divided human population into four groups based on the presence of antigens found in their RBCs. Each group represented a blood group. Thus, there are four types of blood groups - A, B, AB and O. The blood group ‘O’ does not contain any antigen on RBCs and can be given to any person. Hence, this blood group is called a universal donor.