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Question

The net pressure gradient that causes fluid to filter out of the glomeruli into the capsule is


A

20 mm Hg

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B

75 mm Hg

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C

30 mm Hg

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D

5O mm Hg

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Solution

The correct option is A

20 mm Hg


The correct option is A:

The explanation for the correct option:

  1. Net filtration pressure (NFP) is the total effective pressure that promotes glomerular filtration which is Glomerular Hydrostatic pressure(GHP) minus blood colloidal osmotic pressure (BCOP) and Glomerular filtrate pressure (GFP).
  2. NFP = GHP-(BCOP+GFP)

NFP= 70-(30+20)

NFP= 20 mm Hg

The explanation for the incorrect options:

Option B:

  1. 75 mm Hg is hydrostatic pressure in glomerular capillaries that favour glomerular filtration.
  2. The net pressure gradient that causes fluid to filter out of the glomeruli in the capsule is 20 mm Hg.

Option C:

  1. 30 mm Hg is blood colloidal osmotic pressure (BCOP) due to plasma proteins, mainly serum albumin.

Option D:

  1. 50 mm Hg pressure is total pressure that is opposing glomerular filtration (BCOP+GFP).

Final answer: The net pressure gradient that causes fluid to filter out of the glomeruli into the capsule is 20 mm Hg.


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