The correct option is C co-enzymes
The non-proteinaceous substance, which certain enzymes require for their activity are called coenzymes. Coenzymes are organic molecules that are required by certain enzymes to carry out catalysis. They bind to the active site of the enzyme and participate in catalysis but are not considered substrates of the reaction. They function as intermediate carriers of electrons, specific atoms or functional groups that are transferred in the overall reaction. Example: FAD, NAD+, TPP.