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Question

The number of chromosomes in the karyotype of a person with Klinefelter's syndrome is .

A
47
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B
46
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C
45
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D
48
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Solution

The correct option is A 47
Klinefelter's syndrome is caused due to the presence of an additional X chromosome, resulting in a chromosome composition 44 autosomes + XXY (totally, 47 chromosomes). Such an individual exhibits an overall masculine development. However, such individuals could develop breasts upto an extent. The male secondary sexual characters would also be poorly developed, and the individuals would generally be sterile.

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