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Question

The pattern of inheritance of white eye colour in Drosophila shows that the gene is

A
Located at the X-chromosomes
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B
Located on the Y-chromosomes
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C
Located-on an autosome
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D
Sex-linked
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Solution

The correct option is A Located at the X-chromosomes
  • In 1910, Thomas Hunt Morgan performed an experiment that helped identify the role chromosomes play in heredity. That year, Morgan was breeding Drosophila, or fruit flies. After observing thousands of fruit fly offspring with red eyes, he obtained one that had white eyes. Morgan began breeding the white-eyed mutant fly and found that in one generation of flies, the trait was only present in males. Through more breeding analysis, Morgan found that the genetic factor controlling eye color in the flies was on the same chromosome that determined sex. That result indicated that eye color and sex were both tied to chromosomes and helped Morgan and colleagues establish that chromosomes carry the genes that allow offspring to inherit traits from their parents.
  • After observing the white-eye inheritance pattern, Morgan hypothesized that a factor, or gene, controlling eye color was located on the X chromosome. Female flies have two X chromosomes, and males have one X chromosome and one Y chromosome. If a trait, like eye color, correlated with a specific factor on the X chromosome, then the trait was called X-linked. Because males only have one X chromosome, they display all X-linked traits. Females, on the other hand, often need an X-linked trait to exist on both X chromosomes to display that trait. Morgan hypothesized that, in his breeding experiment, the first generation of flies contained males only with white eyes because the gene controlling eye color was on the X chromosome. Males displayed the white eye trait because the trait was present on their only X chromosome. Females did not display the white eye trait because the trait was only present on one of their X chromosomes.

So, the correct answer is 'Located at the X-chromosomes'.

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