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Question

The pesticide, most toxic to vertebrates, is

A
Organochlorine
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B
Organophosphate
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C
Formamidine
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D
None of the above
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Solution

The correct option is C Organophosphate
The toxicity of organophosphates is due to the disruption of the nervous system of a vertebrate through the inhibition of cholinesterase (ChE) enzymes. These enzymes are involved in transmitting normal nerve impulses throughout the nervous system. An acute pesticide dose reduces the activity of ChEs and nerve impulses cannot be transmitted normally. This can paralyze the nervous system and it may lead to death, usually from respiratory failure.

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