The $p K_{a}$ of acetyl salicylic acid (aspirin) is $3.5$ . The pH of gastric juice in human stomach is about $2 - 3$ and the pH in the small intestine is about $8$ . Aspirin will be:

unionised in the small intestine and in the stomach

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completely ionised in the small intestine and in the stomach

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ionised in the stomach and almost unionised in the small intestine

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ionised in the small intestine and almost unionised in the stomach

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Solution

The correct option is D ionised in the small intestine and almost unionised in the stomach
Aspirin (acetylsalicylic acid) is a weak acid. So, in the acidic pH of the stomach, it must be more in unnionised form. In the alkaline pH of the intestine, it must be more in ionised form.

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Q. The pH value of gastric juice in human stomach is about 1.8 and in the small intestine it is about 7.8. The

p K_{a}

, value of aspirin is 3.5. Aspirin will be :

How is required pH maintained in the stomach and small intestine?

Question 4
Which is the correct sequence of parts in a human alimentary canal?

(a) $M o u t h \to s t o m a c h \to s m a l l i n t e s t i n e \to o e s o p h a g u s \to l a r g e i n t e s t i n e$
(b) $M o u t h \to o e s o p h a g u s \to s t o m a c h \to l a r g e i n t e s t i n e \to s m a l l i n t e s t i n e$
(c) $M o u t h \to s t o m a c h \to o e s o p h a g u s \to s m a l l i n t e s t i n e \to l a r g e i n t e s t i n e$
(d) $M o u t h \to o e s o p h a g u s \to s t o m a c h \to s m a l l i n t e s t i n e \to l a r g e i n t e s t i n e$

Which of the following is the correct sequence of parts as they occur in the human alimentary canal ?

(a) Mouth $\to$ Stomach $\to$ Small intestine $\to$ Oesophagus $\to$ Large intestine
(b) Mouth $\to$ Oesophagus $\to$ Stomach $\to$ Large intestine $\to$ Small intestine
(c) Mouth $\to$ Stomach $\to$ Oesophagus $\to$ Small intestine $\to$ Large intestine
(d) Mouth $\to$ Oesophagus $\to$ Stomach $\to$ Small intestine $\to$ Large intestine

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The pKa of acetyl salicylic acid (aspirin) is 3.5. The pH of gastric juice in human stomach is about 2−3 and the pH in the small intestine is about 8. Aspirin will be:

The correct option is D ionised in the small intestine and almost unionised in the stomachAspirin (acetylsalicylic acid) is a weak acid. So, in the acidic pH of the stomach, it must be more in unnionised form. In the alkaline pH of the intestine, it must be more in ionised form.

The $p K_{a}$ of acetyl salicylic acid (aspirin) is $3.5$ . The pH of gastric juice in human stomach is about $2 - 3$ and the pH in the small intestine is about $8$ . Aspirin will be:

The correct option is D ionised in the small intestine and almost unionised in the stomach
Aspirin (acetylsalicylic acid) is a weak acid. So, in the acidic pH of the stomach, it must be more in unnionised form. In the alkaline pH of the intestine, it must be more in ionised form.