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Acidity of Carboxylic Acids

The pKa val...

Question

The $p K_{a}$ values for the three ionizable groups X, Y and Z of glutamic acid $4.3, 9.7 a n d 2.2$ respectively.
The isoelectric point for the amino acid is:

7.00

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3.25

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4.95

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5.95

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Solution

The correct option is D $5.95$
Isoelectric point ( $p^{I}$ ) is the $p^{H}$ at which the overall net charge of the amino acid is zero. So, the average of $p K a$ values relevant to the protonation / depronation of the form with no net charge gives $p^{I}$ .

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Similar questions

Q. The

p K_{a}

values for the three ionisable groups

X, Y and Z

of glutamic acid are 4.3, 9.7 and 2.2 respectively.

The isoelectric point for the amino acid is:

The

p K_{a}

values for the three acidic group

P

Q

R

are

4.3, 9.7

and

2.2

respectively. The isoelectric point of the amino acid is:

Q. Lysine is an amino acid with three ionizable group. These are the

α

-COOH ,

α

- amino and

ε

-amino group with pKa value of

2.2, 9.2

and

10.8

,respectively . The isoelectric point (pI) for Iysine is

The pKa values for the three groups P, Q, R are 4.3, 9.7 and 2.2 respectively. Calculate the isoelectric point of the amino acid rounded to the nearest integer.

In an amino acid, the carboxyl group ionizes at $p K a_{1} = 2.34$ and ammonium ion at $p K a_{2} = 9.6$ . The isoelectric point of the amino acid is at pH.

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The pKa values for the three ionizable groups X, Y and Z of glutamic acid 4.3,9.7and2.2 respectively.The isoelectric point for the amino acid is:

The correct option is D 5.95Isoelectric point (pI) is the pH at which the overall net charge of the amino acid is zero. So, the average of pKa values relevant to the protonation / depronation of the form with no net charge gives pI.

The $p K_{a}$ values for the three ionizable groups X, Y and Z of glutamic acid $4.3, 9.7 a n d 2.2$ respectively.
The isoelectric point for the amino acid is:

The correct option is D $5.95$
Isoelectric point ( $p^{I}$ ) is the $p^{H}$ at which the overall net charge of the amino acid is zero. So, the average of $p K a$ values relevant to the protonation / depronation of the form with no net charge gives $p^{I}$ .