In I quadrant: x > 0, y > 0
In II quadrant: x < 0, y > 0
In III quadrant: x < 0, y < 0
In IV quadrant: x > 0, y < 0
The abscissa and ordinate have the same sign in I and III quadrants whereas the abscissa and ordinate have different signs in II and IV quadrants.
Thus, the points whose abscissa and ordinate have different signs will lie in II and IV quadrants.
Hence, the correct answer is option (d).