The correct option is C lies outside the the circle
Given equation of circle,
x2+y2+2x+8y+1=0
C≡(−1,−4)r=√(−1)2+(−4)2−1=4
Perpendicular distance from center to line 3x+4y−6=0 is p=|3×−1+4×−4−6|√(32+42)=5⇒p>r
Hence, line 3x+4y−6=0 lies outside the circle.