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Question

The potential difference across the membrane of nerve fibre when it does not, show any physiological activity is called resting potential. It is about

A
- 60 mV
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B
- 70 mV
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C
+ 60 mV
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D
+ 90 mV
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Solution

The correct option is B - 70 mV
The resting potential of the axon membrane is the potential difference across it while it is at rest. This is characterised by a negative intracellular fluid and a positive extracellular fluid maintained due to the activity of the sodium-potassium pumps. These pumps actively expel three sodium ions to the extracellular fluid and intake two potassium ions to the intracellular fluid. Due to the presence of immobile negatively charged proteins intracellularly, the potential difference becomes negative and comes out to be -70 mV
Hence, the correct answer is '-70 mV'

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